Physiotens film-coated tablets 0.2mg 28 pcs.

Administration of moxonidine leads to a reduction in systemic vascular resistance and BP.

Indications:

Arterial hypertension.

Contraindications:

• Hypersensitivity to the active substance and other ingredients;
• History of angioedema;
• sinus node weakness syndrome or sinoatrial block;
• severe hepatic insufficiency;
• Severe bradycardia (resting heart rate (HR) less than 50 bpm);
• Grade II or III atrioventricular block;
• Acute and chronic heart failure;
• Breast-feeding period;
• hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption;
• under 18 years of age (due to lack of efficacy and safety data).

How to take, course of treatment and dosage:

Orally, regardless of meals.

In most cases, the starting dose of Physiotens® is 0.2 mg per day. The maximum single dose is 0.4 mg. The maximum daily dose to be divided into 2 doses is 0.6 mg. Individual adjustment of daily dose is necessary depending on patient's tolerance to the therapy. No dose adjustment is required in patients with hepatic impairment.

The starting dose for patients on haemodialysis is 0.2 mg per day. If necessary and if well tolerated, the daily dose may be increased to a maximum of 0.4 mg per day.

In patients with renal insufficiency, a cautious dosage adjustment is recommended, especially at the beginning of treatment. The starting dose should be 0.2 mg daily. If necessary and if well tolerated, daily dose of the drug can be increased to maximum 0.4 mg for patients with moderate renal impairment (CKD more than 30 ml/min, but less than 60 ml/min) and 0.3 mg for patients with severe renal impairment (CKD less than 30 ml/min).

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Physiotens cost is indicated for 1 pack (unit).

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